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Liver : role of the liver in the human body

 What Is Liver?

Liver is a large, roughly triangular organ located in the right upper quadrant of the abdomen. It is the largest gland in the body, weighing approximately 3 pounds, and is responsible for a variety of complex functions, including detoxification and metabolism of nutrients, proteins and hormones. Liver disease, therefore, can refer to any type of damage that affects this vital organ. Liver disease is a broad term that covers all the potential problems that cause liver dysfunction.

Your liver is a large, fatty organ that rests just under your ribs on the right side of your abdomen. It plays a central role in digestion and metabolism. The liver cells perform over 500 known functions, including detoxifying the body, storing energy and producing important proteins for blood clotting and for making hormones. The liver is the only organ in the body that can regenerate itself.

Liver is a large, meaty gland that sits on the right side of the abdomen, just below the ribs. The liver has many functions in the body, but the main function of the liver is to filter the blood coming from the digestive tract, before passing it to the rest of the body. The liver also detoxifies chemicals and metabolizes drugs. As it filters blood, the liver stores nutrients, minerals, and vitamins.

What Is Liver

Liver, the largest gland within the frame, a spongy mass of wedge-fashioned lobes that has many metabolic and secretory capabilities. The liver secretes bile, a digestive fluid; metabolizes proteins, carbohydrates, and fat; stores glycogen, vitamins, and other substances; synthesizes blood-clotting elements; gets rid of wastes and toxic matter from the blood; regulates blood volume; and destroys vintage crimson blood cells.

Liver tissue includes a mass of cells tunneled via bile ducts and blood vessels. Hepatic cells make up about 60 percent of the tissue and carry out greater metabolic features than another institution of cells in the frame. A 2nd group of cells, called Kupffer cells, line the smallest channels of the liver’s vascular machine and play a function in blood formation, antibody production, and ingestion of overseas particles and mobile particles.

Each day the liver secretes about 800 to at least one,000 ml (approximately 1 quart) of bile, which contains bile salts wanted for the digestion of fats inside the weight loss program. Bile is also the medium for excretion of sure metabolic waste products, pills, and poisonous substances. From the liver a duct gadget carries bile to the common bile duct, which empties into the duodenum of the small gut and which connects with the gallbladder, in which it's far concentrated and saved. The presence of fat in the duodenum stimulates the go with the flow of bile out of the gallbladder and into the small gut. Senescent (worn-out) crimson blood cells are destroyed in the liver, spleen, and bone marrow. A pigment, bilirubin, shaped inside the technique of hemoglobin breakdown, is released into the bile, growing its characteristic greenish orange color, and is excreted from the body through the gut.

The liver cells synthesize a number of enzymes. As blood flows via the liver, both from the portal vein and from the hepatic artery, the cells and enzymes are filtered. Nutrients getting into the liver from the intestine are modified into paperwork which might be usable by the frame cells or are stored for future use. Fats are converted into fatty acids after which into carbohydrates or ketone our bodies and transported with the aid of the blood to the tissues, where they're further metabolized. Sugars are transformed into glycogen, which remains saved inside the liver till it's far wished for power manufacturing; it's miles then reconverted into glucose and launched into the bloodstream. The liver manufactures blood serum proteins, which includes albumin and several clotting factors, and substances them to the blood. The liver also metabolizes nitrogenous waste products and detoxifies toxic substances, making ready them for removal within the urine or.

A common sign of impaired liver function is jaundice, a yellowness of the eyes and pores and skin bobbing up from immoderate bilirubin within the blood. Jaundice can end result from an abnormally excessive degree of purple bloodmobile destruction (hemolytic jaundice), faulty uptake or delivery of bilirubin through the hepatic cells (hepatocellular jaundice), or a blockage inside the bile duct gadget (obstructive jaundice). Failure of hepatic cells to function can result from hepatitis, cirrhosis, tumors, vascular obstruction, or poisoning. Symptoms may additionally consist of weak spots, low blood pressure, clean bruising and bleeding, tremor, and accumulation of fluid inside the abdomen. Blood assessments can display bizarre levels of bilirubin, ldl cholesterol, serum proteins, urea, ammonia, and diverse enzymes. A precise analysis of a liver hassle may be set up by means of performing a needle biopsy.

The liver is challenged by a variety of other disorders and illnesses. Abscesses may be because of acute appendicitis; those going on inside the bile ducts may additionally result from gallstones or may comply with surgical operation. The parasite that reasons amebic dysentery within the tropics can produce liver abscesses as properly. Various different parasites typical in unique elements of the sector additionally infect the liver. Liver most cancers are commonplace, going on on the whole as secondary tumors originating elsewhere in the frame. Glycogen-garage sicknesses, a collection of hereditary problems, generate a buildup of glycogen in the liver and an insufficient delivery of glucose within the blood. Certain pills may damage the liver, generating jaundice.

Digestive system

  1. Digestive system

The structure of the liver in the human body

  • The liver is one of the largest organs in the human body, and is essential to the function of the digestive system. The liver has many important functions, including filtering toxins from the blood, producing bile to help with the digestion of fats, and storing nutrients. The liver is made up of two main lobes, the right lobe and the left lobe. The right lobe is larger than the left lobe, and is divided into four sections: the quadrate lobe, the caudate lobe, the anterior lobe, and the posterior lobe.

  • The liver is a reddish-brown, wedge-fashioned organ with  lobes of unequal length and form. A human liver generally weighs approximately 1.5 kg (three.3 lb) and has a width of approximately 15 cm (6 in). There is vast length version between people, with the usual reference variety for men being 970–1,860 g (2.14–four.10 lb) and for girls 600–1,770 g (1.32–3.Ninety lb).[12] It is each the heaviest internal organ and the most important gland inside the human body. Located inside the proper upper quadrant of the stomach hollow space, it rests just below the diaphragm, to the proper of the stomach and overlies the gallbladder.

  • The liver is connected to two big blood vessels: the hepatic artery and the portal vein. The hepatic artery carries oxygen-rich blood from the aorta thru the celiac trunk, while the portal vein contains blood rich in digested vitamins from the whole gastrointestinal tract and also from the spleen and pancreas. These blood vessels subdivide into small capillaries referred to as liver sinusoids, which then lead to lobules.

  • Lobules are the functional units of the liver. Each lobule is made from tens of millions of hepatic cells (hepatocytes), which are the basic metabolic cells. The lobules are held together by means of a first-rate, dense, irregular, fibroelastic connective tissue layer extending from the fibrous capsule covering the whole liver called Glisson's tablet. This extends into the shape of the liver with the aid of accompanying the blood vessels, ducts, and nerves at the hepatic hilum. The complete floor of the liver, besides for the bare vicinity, is blanketed in a serous coat derived from the peritoneum, and this firmly adheres to the internal Glisson's tablet.

The following are some of the most essential person components of the liver:

  • Common Hepatic Duct: A tube that incorporates bile out of the liver. It is fashioned from the intersection of the right and left hepatic ducts.

  • Falciform Ligament: A skinny, fibrous ligament that separates the 2 lobes of the liver and connects it to the belly wall.

  • Glisson’s Capsule: A layer of loose connective tissue that surrounds the liver and its associated arteries and ducts.

  • Hepatic Artery: The primary blood vessel that materials the liver with oxygenated blood.

  • Hepatic Portal Vein: The blood vessel that consists of blood from the gastrointestinal tract, gallbladder, pancreas, and spleen to the liver. 

  • Lobes: The anatomical sections of the liver.

  • Lobules: Microscopic constructing blocks of the liver.

  • Peritoneum: A membrane overlying the liver that paperwork the outside.

What is the role of the liver in the human body?

The liver is a large and important organ in the human body. The liver is responsible for processing and cleansing the blood. The liver also helps to create blood proteins and enzymes. The liver is also involved in the production of bile, which helps to digest food.

The liver is a major organ in the human body. It is responsible for breaking down and distributing food, water, and other substances in the body. The liver also filters blood and produces enzymes to help with many metabolic processes.

The liver is a vital organ of the body that performs over 500 critical capabilities. These encompass casting off waste products and foreign substances from the bloodstream, regulating blood sugar tiers, and growing essential vitamins. Here are a number of its maximum vital functions:


  • Albumin Production: Albumin is a protein that keeps fluids within the bloodstream from leaking into surrounding tissue. It also consists of hormones, nutrients, and enzymes through the body.

  • Bile Production: Bile is a fluid that is essential to the digestion and absorption of fat within the small intestine.

  • Filters Blood: All the blood leaving the stomach and intestines passes through the liver, which removes pollution, byproducts, and different harmful substances.

  • Regulates Amino Acids: The production of proteins rely upon amino acids. The liver makes certain amino acid ranges within the bloodstream continue to be healthy.

  • Regulates Blood Clotting: Blood clotting coagulants are created using the use of nutrition K, which can only be absorbed with the help of bile, a fluid the liver produces.

  • Resists Infections: As part of the filtering system, the liver also removes microorganisms from the bloodstream.

  • Stores Vitamins and Minerals: The liver stores enormous quantities of vitamins A, D, E, K, and B12, as well as iron and copper.

  • Processes Glucose: The liver gets rid of extra glucose (sugar) from the bloodstream and shops it as glycogen. As wanted, it could convert glycogen back into glucose.

Maintaining the health of the liver in the human body

The liver is a large and multifunctional organ that is essential to the health of the human body. Its main functions include filtering toxins from the blood, producing bile to aid in digestion, storing energy in the form of glycogen, and synthesizing proteins. The liver also plays a role in metabolism, hormone production, and immunity. Because of its many functions, the liver is susceptible to a variety of diseases and disorders that can have serious consequences for the health of the individual.

The liver is the largest internal organ in the human body. It has many functions, including detoxification, protein synthesis, and the production of biochemicals necessary for digestion. The liver also plays a role in metabolism, the regulation of hormones, and the storage of glycogen, vitamins, and minerals. The liver is a vital organ, and its health is essential to the health of the entire body.

The first-rate way to keep away from liver sickness is to take energetic steps towards a wholesome existence. The following are some suggestions in order to help keep the liver functioning as it must:


  • Avoid Illicit Drugs: Illicit drugs are pollutants that the liver should clear out. Taking these pills can motivate long-term damage.

  • Drink Alcohol Moderately: Alcohol must be broken down by using the liver. While the liver can moderate amounts, immoderate alcohol use can cause harm.

  • Exercise Regularly: A normal exercise routine will help promote well known fitness for each organ, which includes the liver.

  • Eat Healthy Foods: Eating immoderate fat can make it difficult for the liver to function and result in fatty liver disorder.

  • Practice Safe Sex: Use protection to avoid sexually transmitted illnesses such as hepatitis C.

  • Vaccinate: Especially when traveling, get suitable vaccinations against hepatitis A and B, in addition to illnesses such as malaria and yellow fever, which develop inside the liver.

Liver transplant

Liver transplant is the surgical procedure in which an organ of a patient (the source) is placed into the body of another individual (the recipient).In liver transplant, only the liver is transplanted.The surgery involves removal of a portion or all of the liver from a donor, and then placing it into a recipient’s body.After surgery, both individuals are closely monitored and observed for signs of complications.

A liver transplant is a surgical procedure that replaces a liver damaged by disease or injury with a healthy organ.Most commonly, the new liver comes from someone who has died (cadaveric), but it can also come from a living donor.A liver that has been removed from an adult is called an adult-to-adult (ATAD) transplant, while one from a child is called an infant-to-adult (ITAD) transplant.

  1.  Medical And Anatomical Concept Of The Human Body
  2.  Diseases Diagnosis and Treatment-A/Z
  3. Medical Specialties
  4. Organ surgery : Detailed explanation
  5. Diagnosis And Medical Examinations


Liver : role of the liver in the human body

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